TAF2 Antibody, FITC conjugated

Code CSB-PA747395LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TAF2 Polyclonal antibody
Uniprot No.
Target Names
TAF2
Alternative Names
TAF2 antibody; CIF150 antibody; TAF2B antibody; Transcription initiation factor TFIID subunit 2 antibody; 150 kDa cofactor of initiator function antibody; RNA polymerase II TBP-associated factor subunit B antibody; TBP-associated factor 150 kDa antibody; Transcription initiation factor TFIID 150 kDa subunit antibody; TAF(II)150 antibody; TAFII-150 antibody; TAFII150 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription initiation factor TFIID subunit 2 protein (400-450AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter.
Gene References into Functions
  1. the TAF2-TAF8-TAF10 complex demonstrates that there is a stepwise assembly pathway of nuclear holo-TFIID, regulated by nuclear import of preformed cytoplasmic submodules PMID: 25586196
  2. This study suggested that the Microcephaly thin corpus callosum intellectual disability syndrome is caused by the more conserved mutation p.Thr186Arg, with the second sequence change identified, p.Pro416His. PMID: 24084144
Involvement in disease
Mental retardation, autosomal recessive 40 (MRT40)
Subcellular Location
Nucleus.
Protein Families
TAF2 family
Tissue Specificity
Expressed in all tissues tested.
Database Links

HGNC: 11536

OMIM: 604912

KEGG: hsa:6873

STRING: 9606.ENSP00000367406

UniGene: Hs.122752

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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